active transport
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Facilitated diffusion, particularly the operation of the sodium-potassium pump, would be most affected by a disorder causing damage to carrier proteins. Diseases like Alzheimer's and Parkinson's have been linked to abnormalities in proteins, leading to devastating effects. ;
Damage to carrier proteins would most significantly affect active transport mechanisms in cells. Active transport requires these proteins to move substances against their concentration gradients, which is energy-dependent. Without functional carrier proteins, essential cellular processes would be disrupted, influencing cell health and function.
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