A nurse is preparing to administer medications to an older adult client. The nurse should identify that which of the following physiologic changes can affect the distribution of medications in the older adult client?
A. Decreased renal blood flow
B. Increased gastric pH
C. Decreased hepatic mass
D. Increased body fat compared to muscle mass

Question

Anonymous · Answer

The correct answer is D: Increased body fat compared to muscle mass, which significantly affects the distribution of medications in older adults. This change alters the volume of distribution for fat-soluble drugs, potentially leading to prolonged effects or toxicity. Other factors like decreased hepatic mass and increased gastric pH also play roles, but the increased body fat is especially impactful. 
 ;

GinnyAnswer · Answer

Physiologic changes in older adults, including increased body fat and decreased hepatic mass, significantly affect medication distribution. Increased gastric pH can also influence drug absorption. Recognizing these changes is crucial for the safe administration of medications. ;

Answered by GinnyAnswer | 2025-07-08

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